Protein Folding, Misfolding, and Disorder
Lecture no. 5 from the course: Biochemistry and Molecular Biology: How Life Works
Taught by Professor Kevin Ahern | 32 min | Categories: The Great Courses Plus Online Science Course
Discover how proteins fold into complex shapes, often with the help of molecular chaperones. Then learn the deadly consequences of proteins that do not fold properly, leading to degenerative conditions such as Alzheimer’s, Parkinson’s, and prion diseases. Also look at intrinsically disordered proteins, which lack a fixed structure, permitting flexible interactions with other biomolecules.